A straightforward and efficient synthetic access to biologically active marine sesterterpenoids, sesterstatins 4 and 5.
نویسندگان
چکیده
A straightforward and efficient synthesis of sesterstatins 4 and 5 is reported, in which the reductive Heck cyclisation was employed as the key step for constructing the D ring.
منابع مشابه
Over Expression of Biologically Active Interferon Beta Using Synthetic Gene in E. coli
In this study, our previously reported novel synthetic gene encoding 166 residues of interferon-? was used for an efficient expression of IFN-?. The synthetic gene was cloned into pET21a expression vector and transferred into E. coli. Recombinant protein was over-expressed in the E. coli. Identity of the recombinant protein was confirmed by western blot analysis. The recombinant protein was bio...
متن کاملHighly efficient synthesis of tetrahydrobenzo[b]pyrans under visible light promoted by cesium carbonate
Multi-component coupling reaction (MCR) is a powerful synthetic tool for the synthesis of biologically active compounds. Development of such multi-component coupling reaction strategies in visible light has been of considerable interest, as they provide simple and rapid access to a large number of organic molecules through a sustainable path. An efficient and green protocol for the synthesis of...
متن کاملSodium Bismuthate: An Efficient Catalyst for the One-pot Synthesis of Biologically Active Spiro[4H-pyran] Derivativesunder Solvent-free Conditions
An efficient sodium bismuthate (NaBiO3) synthesis of biologically active spiro[4H-pyran]derivatives has been accomplished via one-pot three-condensation of isatin/acenaphthequinone, malononitrile and different reagents including 1,3-dicrbonyl compounds, α-naphthol and 4-hydroxycumarin under solvent-free conditions. The notable advantages of the present procedure are: eco-friendly, environmental...
متن کاملInfluence of Natural Sources of Biologically Active Substances on Livestock and Poultry Reproduction
Synthetic hormones and bioactive substances (vitamins, pigments and isoflavons) which have been used in the feed industry are accumulated in milk, meat and eggs. It is suspected that these are responsible for a number of side-effects such as carcinogenesis, liver and kidney damage, allergies in consumers. Furthermore the synthetic hormones, vitamins, pigments are less active than those extracte...
متن کاملOne pot, Five-component Synthesis of Functionalized Piperidines Using Zn(OAc)2.2H2O as a Highly Efficient Catalyst
A convenient synthetic route for the synthesis of biologically active functionalized piperidines usingZn(OAc)2.2H2O as a highly efficient catalyst via five-component reaction of aromatic aldehydes,anilines and β-ketoesters at ambient temperature has studied. Mild reaction conditions, simplicity ofoperation and work-up procedures with no necessity of chromatographic purification steps, theavaila...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Chemical communications
دوره 47 10 شماره
صفحات -
تاریخ انتشار 2011